NLRP12 (6C12) Mouse Monoclonal Antibody

货号: BD-PB3811
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规格 价格 期货 数量
  • 50μl
    1100.00
    现货
    100μl
    2000.00
    现货

产品基本信息

  • 产品货号 BD-PB3811
  • 别名 NACHT, LRR and PYD domains-containing protein 12, Monarch-1, PYRIN-containing APAF1-like protein 7, Regulated by nitric oxide, NLRP12, NALP12, PYPAF7, RNO
  • 产品名称 NLRP12 (6C12) Mouse Monoclonal Antibody
  • 类别 抗原抗体
  • Clonality Monoclonal
  • 推荐应用 WB
  • 反应种属 Human, Mouse
  • Human Gene ID NP_001264055.1;NP_001264058.1;NP_653288.1
  • 特异性 This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.
  • 稀释度 WB 1:500
  • 预测分子量 120kDa
  • 同种型 IgM,κ
  • 背景介绍 This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
  • 组织表达 Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes.
  • 细胞定位 Cytoplasm.

图片

All lanes : Anti-NLRP12 Antibody at 1:500 dilution + mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 120 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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