产品基本信息

• 产品货号 BD-PB3811
• 别名 NACHT, LRR and PYD domains-containing protein 12, Monarch-1, PYRIN-containing APAF1-like protein 7, Regulated by nitric oxide, NLRP12, NALP12, PYPAF7, RNO
• 产品名称 NLRP12 (6C12) Mouse Monoclonal Antibody
• 类别 抗原抗体
• Clonality Monoclonal
• 推荐应用 WB
• 反应种属 Human, Mouse
• Human Gene ID NP_001264055.1;NP_001264058.1;NP_653288.1
• 特异性 This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.
• 稀释度 WB 1:500
• 预测分子量 120kDa
• 同种型 IgM,κ
• 背景介绍 This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
• 组织表达 Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes.
• 细胞定位 Cytoplasm.

图片

All lanes : Anti-NLRP12 Antibody at 1:500 dilution + mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 120 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

产品详情