产品基本信息

• 产品货号 RM6854
• 别名 Adrenodoxin; ADX; FDX; fdx1; Ferredoxin 1; Hepatoredoxin; LOH11CR1D;
• 产品名称 FDX1 / ADX (18G16) Rabbit Monoclonal Antibody
• 类别 抗原抗体
• 基因名称 FDX1
• 蛋白名称 ADX
• Clonality Monoclonal
• 推荐应用 WB
• 反应种属 Human,Mouse,Rat
• 存储缓冲液 Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
• Human Gene ID 2230
• 免疫原 A synthetic peptide of human Adrenodoxin
• 稀释度 WB 1:1000-1:5000
• 参考分子量 14kDa
• 预测分子量 19kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 IgG
• 注意事项 FDX1 / ADX Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
• 组织表达 Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level)
• 细胞定位 Mitochondrion matrix
• 功能 Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783). Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783). Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783). Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).

图片

Western blot detection of Adrenodoxin in 3T3 cell lysates using Adrenodoxin antibody(1:1000 diluted).

产品详情