产品基本信息
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产品货号
RM4909
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别名
CMT2L; CRYAC; DHMN2; E2IG1; H11; HMN2; HSPB8; HSP22;
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产品名称
HSPB8/HSP22 (14N5) Rabbit Monoclonal Antibody
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类别
抗原抗体
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基因名称
HSPB8
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蛋白名称
CRYAC, E2IG1, HSP22
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,IHC-F,IF-ICC,IF-P,IF-F
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反应种属
Human,Mouse,Rat
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存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Human Gene ID
26353
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稀释度
WB 1:1000-1:2000,IHC-P/IHC-F 1:100-1:200,IF-ICC 1:50-1:200,IF-P/IF-F 1:50-1:200
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参考分子量
22kDa
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预测分子量
22kDa
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宿主
Rabbit
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同种型
IgG
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注意事项
HSPB8/HSP22 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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组织表达
Predominantly expressed in skeletal muscle and heart.
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细胞定位
Cytoplasm. Nucleus Note=Translocates to nuclear foci during heat shock
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功能
Displays temperature-dependent chaperone activity.
图片
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Western blot analysis of HSPB8/HSP22 expression in Human fetal heart lysate. |
产品详情
HSPB8 (HSP22) is a member of the small heat shock protein superfamily and the human protein is most closely related to HSP27. Similar to most other small HSPs (sHSPs), HSPB8 is predominantly transcribed in skeletal muscle and heart. In a two hybrid screen, HSPB8 interacted preferentially with a triple aspartate form of HSP27 which mimics HSP27 phosphorylated at Ser15, Ser78, and Ser82, as compared to wild-type HSP27.