c-Myc (9U18) Rabbit Monoclonal Antibody

货号: RM4176

1200.00

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产品基本信息

  • 产品货号 RM4176
  • 别名 c-Myc; Class E basic helix-loop-helix protein 39; MRTL; MYC; Myc proto-oncogene protein; v-myc;
  • 产品名称 c-Myc (9U18) Rabbit Monoclonal Antibody
  • 纯度 Affinity-chromatography
  • 类别 抗原抗体
  • 基因名称 MYC
  • 蛋白名称 BHLHE39
  • 推荐应用 WB,IHC,ICC/IF,FC,IP
  • 反应种属 Human,Mouse,Rat
  • 存储缓冲液 Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID 4609
  • Human Swissprot No. P01106
  • 免疫原 A synthetic peptide of human c-Myc
  • 稀释度 WB 1:2000, IHC 1:200, ICC/IF 1:100, FCM 1:100, IP 1:50
  • 参考分子量 57-65kDa
  • 预测分子量 49kDa
  • 同种型 Rabbit IgG
  • 注意事项 c-Myc Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 细胞定位 Nucleus, nucleoplasm. Nucleus, nucleolus
  • 功能 Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).
  • 期货 现货
  • Clonality Monoclonal

图片

Western blot detection of c-Myc in HeLa cell lysates using c-Myc antibody(1:1000 diluted).
Western blot detection of c-Myc in K562,C6,3T3,Hela cell lysates using c-Myc antibody(1:1000 diluted).

产品详情

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Myc a proto-oncogenic transcription factor that plays a role in cell proliferation, apoptosis and in the development of human tumors.. Seems to activate the transcription of growth-related genes.

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