产品基本信息
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产品货号
BDAF0013
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别名
Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
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产品名称
Recombinant Human CD47 (C-6His)
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类别
诊断原料
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推荐应用
Dependent by end user
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存储缓冲液
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
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Human Swissprot No.
Q08722
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参考分子量
30-45kDa, reducing conditions
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预测分子量
14.5kDa
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运输及保存条件
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
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表达系统
human cells
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内毒素
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
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宿主
human cells
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背景介绍
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
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产品描述
Recombinant Human Leukocyte Surface Antigen CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a 6His tag at the C-terminus.
产品详情
Recombinant Human Leukocyte Surface Antigen CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a 6His tag at the C-terminus.