产品基本信息

• 产品货号 BDAB0061
• 别名 Transmembrane protease serine 2,Serine protease 10.
• 产品名称 Recombinant Human TMPRSS2 protein
• 类别 病原微生物抗原抗体假病毒
• 推荐应用 Immunogen
• 存储缓冲液 Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
• 特异性 Homo sapiens (Human)
• 参考分子量 25.65 kDa
• 运输及保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
• 宿主 E.coli
• type1 His tag
• 注意事项 TMPRSS2
• limitation For?research?use?only?.
• 背景介绍 Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.
• 纯化 >90% as determined by SDS-PAGE

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产品详情