产品基本信息

• 产品货号 BDAB0057
• 别名 ACE-related carboxypeptidase,Angiotensin-converting enzyme homolog,Metalloprotease MPROT15
• 产品名称 Recombinant Human ACE2 protein
• 类别 病原微生物抗原抗体假病毒
• 推荐应用 Immunogen
• 存储缓冲液 Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
• 特异性 Homo sapiens (Human)
• 参考分子量 42.71kDa
• 运输及保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
• 宿主 E.coli
• type1 N-His
• 注意事项 ACE2
• limitation For research use only .Not for use in clinical diagnostic procedures.
• 背景介绍 Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
• 纯化 >90% as determined by SDS-PAGE

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