产品基本信息

• 产品货号 BD-PB2131
• 别名 26S proteasome non-ATPase regulatory subunit 7, 26S proteasome regulatory subunit RPN8, 26S proteasome regulatory subunit S12, Mov34 protein homolog, Proteasome subunit p40, PSMD7, MOV34L
• 产品名称 PSMD7 Rabbit Polyclonal Antibody (C-term)
• 类别 抗原抗体
• Clonality Polyclonal
• 推荐应用 WB, IHC-P, FCM
• 反应种属 Human
• Human Gene ID NP_002802.2
• 特异性 This PSMD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the C-terminal region of human PSMD7.
• 稀释度 WB 1:1000, IHC-P 1:100-500, FCM 1:10-50
• 预测分子量 37kDa
• 宿主 Rabbit
• 同种型 IgG
• 背景介绍 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD7 is a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
• 纯化 Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

图片

	PSMD7 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PSMD7 antibody detected the PSMD7 protein (arrow).
	PSMD7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PSMD7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	PSMD7 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

产品详情