产品基本信息
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产品货号
BD-PA1243
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别名
SYNI; SYN1a; SYN1b
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产品名称
SYN1 Mouse Monoclonal Antibody
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类别
抗原抗体
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基因名称
SYN1
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,ICC,FCM,Elisa
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反应种属
Human,Mouse,Monkey,Rat
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存储缓冲液
Purified antibody in PBS with 0.05% New type preservative N
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Human Gene ID
6853
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免疫原
Purified recombinant fragment of human SYN1 (AA: 362-511) expressed in E. Coli.
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稀释度
WB 1:500-1:2000, IHC-P 1:200-1:1000, ICC 1:200-1:1000, FCM 1:200-1:400, ELISA 1:10000
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参考分子量
74.1kDa
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运输及保存条件
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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宿主
Mouse
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同种型
IgG1
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克隆号
7H10G6
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期货
3个工作日
图片
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) |
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Western blot analysis using SYN1 mouse mAb against SK-N-SH (1), NIH/3T3 (2), U251 (3), C6 (4), A549 (5), MCF-7 (6), and COS7 (7) cell lysate. |
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Immunofluorescence analysis of GC-7901 cells. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503) |
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Immunofluorescence analysis of GC-7901 cells using SYN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503) |
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Immunofluorescence analysis of HepG2 cells. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503) |
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Immunofluorescence analysis of HepG2 cells using SYN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503) |
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Flow cytometric analysis of Hela cells using SYN1 mouse mAb (green) and negative control (red). |
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Immunohistochemical analysis of paraffin-embedded human testis tissues using SYN1 mouse mAb with DAB staining. |
产品详情
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.