博奥龙

登录 注册
首页 产品中心 抗体产品 常规一抗 未标记一抗 MAP2K2 Mouse Monoclonal Antibody

MAP2K2 Mouse Monoclonal Antibody

评论 (0) 文献 说明书
试用装
货号: BD-PA0009
收藏
规格 价格 货期 数量
  • 50μl
    1400.00
    咨询
    100μl
    2500.00
    咨询
产品详情 相关文献 产品问答 相关产品 留言和评论

产品基本信息

  • 产品货号 BD-PA0009
  • 别名 MEK2; MKK2; MAPKK2
  • 产品名称 MAP2K2 Mouse Monoclonal Antibody
  • 类别 抗体产品
  • 基因名称 MAP2K2
  • Clonality Monoclonal
  • 推荐应用 WB,ICC,FCM,Elisa
  • 反应种属 Human,Mouse,Rat
  • 存储缓冲液 Ascitic fluid containing 0.03% New type preservative N.
  • Human Gene ID 5605
  • 免疫原 Purified recombinant fragment of human MAP2K2 expressed in E. Coli.
  • 稀释度 WB 1:500-1:2000, ICC 1:200-1:1000, FCM 1:200-1:400, ELISA 1:10000
  • 参考分子量 44kDa
  • 运输及保存条件 Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
  • 宿主 Mouse
  • 同种型 IgG1
  • 克隆号 7F5
  • 纯度 crude ascites

图片

Western blot analysis using MAP2K2 mouse mAb against PC-12 (1), Jurkat (2), Hela (3) and NIH/3T3 (4) cell lysate.
Immunofluorescence analysis of Hela cells using anti-MAP2K2 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Flow cytometric analysis of Hela cells using anti-MAP2K2 mAb (green) and negative control (purple).

产品详情

MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax.

文献引用 (0)

产品问答

内容已折叠

相关产品

内容已折叠

最新浏览的产品

评论内容：
上传图片：
商品评价：
提交评论
« »