DKK3 Mouse Monoclonal Antibody

货号: BD-PA0010

2500.00

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产品基本信息

  • 产品货号 BD-PA0010
  • 别名 RIG; REIC
  • 产品名称 DKK3 Mouse Monoclonal Antibody
  • 类别 抗原抗体
  • 基因名称 DKK3
  • Clonality Monoclonal
  • 推荐应用 WB,FCM,Elisa
  • 反应种属 Human,Monkey
  • 存储缓冲液 Ascitic fluid containing 0.03% New type preservative N.
  • Human Gene ID 27122
  • 免疫原 Purified recombinant fragment of human DKK3 expressed in E. Coli.
  • 稀释度 WB 1:500-1:2000, FCM 1:200-1:400, ELISA 1:10000
  • 参考分子量 38kDa
  • 运输及保存条件 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
  • 宿主 Mouse
  • 同种型 IgG1
  • 克隆号 4G7
  • 期货 3个工作日

图片

Western blot analysis using DKK3 mouse mAb against HEK293 (1), MCF-7 (2) and HL7702 (3) cell lysate.
Flow cytometric analysis of MCF-7 cells using anti-DKK3 mAb (green) and negative control (purple).

产品详情

Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

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