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ZBTB7B Mouse Monoclonal Antibody

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货号: BD-PA0011
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规格 价格 货期 数量
  • 50μl
    1400.00
    3个工作日
    100μl
    2500.00
    3个工作日
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产品基本信息

  • 产品货号 BD-PA0011
  • 纯度 crude ascites
  • 别名 THPOK; ZFP67; ZBTB15; c-Krox; hcKrox; ZNF857B; DKFZp686G01254; ZBTB7B
  • 产品名称 ZBTB7B Mouse Monoclonal Antibody
  • 类别 抗体产品
  • 基因名称 ZBTB7B
  • Clonality Monoclonal
  • 推荐应用 WB,IHC-P,ICC,Elisa
  • 反应种属 Human
  • 存储缓冲液 Ascitic fluid containing 0.03% New type preservative N.
  • Human Gene ID 51043
  • 免疫原 Purified recombinant fragment of human ZBTB7B expressed in E. Coli.
  • 稀释度 WB 1:500-1:2000, IHC-P 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:10000
  • 参考分子量 58kDa
  • 运输及保存条件 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
  • 宿主 Mouse
  • 同种型 IgG1
  • 克隆号 7C12

图片

Western blot analysis using ZBTB7B mAb against HEK293 (1,2) cell lysate.
Immunofluorescence analysis of Hela cells using ZBTB7B mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin
Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B mouse mAb

产品详情

ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

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