ZBTB7B Mouse Monoclonal Antibody

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说明书

货号: BD-PA0011

￥2500.00

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产品基本信息

产品货号 BD-PA0011
别名 THPOK; ZFP67; ZBTB15; c-Krox; hcKrox; ZNF857B; DKFZp686G01254; ZBTB7B
产品名称 ZBTB7B Mouse Monoclonal Antibody
类别抗原抗体
基因名称 ZBTB7B
Clonality Monoclonal
推荐应用 WB,IHC-P,ICC,Elisa
反应种属 Human
存储缓冲液 Ascitic fluid containing 0.03% New type preservative N.
Human Gene ID 51043
免疫原 Purified recombinant fragment of human ZBTB7B expressed in E. Coli.
稀释度 WB 1:500-1:2000, IHC-P 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:10000
参考分子量 58kDa
运输及保存条件 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
宿主 Mouse
同种型 IgG1
克隆号 7C12
期货 3个工作日

图片

	Western blot analysis using ZBTB7B mAb against HEK293 (1,2) cell lysate.
	Immunofluorescence analysis of Hela cells using ZBTB7B mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin
	Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B mouse mAb

产品详情

ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

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