产品基本信息
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产品货号
BD-PA0078
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别名
CCK4; PTK7
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产品名称
PTK7 Mouse Monoclonal Antibody
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类别
抗原抗体
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基因名称
PTK7
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,Elisa
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反应种属
Human
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存储缓冲液
Ascitic fluid containing 0.03% New type preservative N.
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Human Gene ID
5754
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免疫原
Purified recombinant fragment of human PTK7 expressed in E. Coli.
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稀释度
WB 1:500-1:2000, IHC-P 1:200-1:1000, ELISA 1:10000
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参考分子量
118kDa
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运输及保存条件
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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宿主
Mouse
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同种型
IgG1
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克隆号
4F9
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期货
3个工作日
图片
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Western blot analysis using PTK7 mouse mAb against Hela (1), A431 (2), HCT116 (3), Caco2 (4), HepG2 (5) and MCF-7 (6) cell lysate. |
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Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using PTK7 mouse mAb with DAB staining. |
产品详情
Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.
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