产品基本信息

• 产品货号 BD-PT1201
• 别名 CYP26C1; Cytochrome P450 26C1
• 产品名称 CYP26C1 Rabbit Polyclonal Antibody
• 类别 抗原抗体
• 基因名称 CYP26C1
• 蛋白名称 Cytochrome P450 26C1
• Clonality Polyclonal
• 推荐应用 IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Rat,Mouse
• 浓度 1 mg/ml
• 存储缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
• Human Gene ID 340665
• Human Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=340665
• Human Swissprot Link http://www.uniprot.org/uniprotkb/Q6V0L0/entry
• 免疫原 The antiserum was produced against synthesized peptide derived from human CYP26C1. AA range:41-90
• 特异性 CYP26C1 Polyclonal Antibody detects endogenous levels of CYP26C1 protein.
• 稀释度 IHC-P 1:100-1:300, ELISA 1:40000, IF-P/IF-F/IF-ICC 1:50-200
• 参考分子量 57kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 Rabbit,IgG
• 背景介绍 cytochrome P450 family 26 subfamily C member 1(CYP26C1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008],
• 组织表达 Detected in most tissues at very low level.
• 细胞定位 Membrane ; Single-pass membrane protein .
• 信号通路 Retinol metabolism;
• 功能 cofactor:Heme group.,function:Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).,induction:By retinoic acid.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Detected in most tissues at very low level.,
• 纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

图片

	Immunohistochemistry analysis of paraffin-embedded human brain, using Cytochrome P450 26C1 Antibody. The picture on the right is blocked with the synthesized peptide.
	Western blot analysis of the lysates from HeLa cells using Ik3-1 antibody.

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