产品基本信息

• 产品货号 BD-PT1079
• 别名 COX7A2P2; COX7A3; COX7AL2; COX7AP2; Putative cytochrome c oxidase subunit 7A3; mitochondrial; Cytochrome c oxidase subunit VIIa 3; COX7A2; COX7AL; Cytochrome c oxidase subunit 7A2, mitochondrial; Cytochrome c oxidase subunit VIIa-liver/hear
• 产品名称 COX7a2/3 Rabbit Polyclonal Antibody
• 类别 抗原抗体
• 基因名称 COX7A2/COX7A2P2
• 蛋白名称 Cytochrome c oxidase subunit 7A2/3 mitochondrial
• Clonality Polyclonal
• 推荐应用 WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Mouse,Rat
• 浓度 1 mg/ml
• 存储缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
• Human Gene ID 1347
• Human Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1347
• Human Swissprot Link http://www.uniprot.org/uniprotkb/O60397/entry
• Mouse Gene ID 12866
• Mouse Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12866
• Rat Gene ID 29507
• Rat Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29507
• Rat Swissprot No. P35171
• Rat Swissprot Link http://www.uniprot.org/uniprot/P35171
• 免疫原 The antiserum was produced against synthesized peptide derived from human COX7S/A2. AA range:1-50
• 特异性 COX7a2/3 Polyclonal Antibody detects endogenous levels of COX7a2/3 protein.
• 稀释度 WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:10000, IF-P/IF-F/IF-ICC 1:50-200
• 预测分子量 12kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 Rabbit,IgG
• 背景介绍 Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.
• 细胞定位 Mitochondrion inner membrane .
• 纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

图片

	Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using COX7S/A2 Antibody. The picture on the right is blocked with the synthesized peptide.
	Western blot analysis of lysates from rat heart cells, using COX7S/A2 Antibody. The lane on the right is blocked with the synthesized peptide.
	The nature compound dehydrocrenatidine exerts potent antihepatocellular carcinoma by destroying mitochondrial complexes in vitro and in vivo 2022 Feb 02. WB Human

产品详情