产品基本信息

• 产品货号 BD-PT0939
• 别名 CKS1B; CKS1; PNAS-143; PNAS-16; Cyclin-dependent kinases regulatory subunit 1; CKS-1
• 产品名称 Cks1 Rabbit Polyclonal Antibody
• 类别 抗体产品
• 基因名称 CKS1B
• 蛋白名称 Cyclin-dependent kinases regulatory subunit 1
• Clonality Polyclonal
• 推荐应用 WB,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Mouse
• 浓度 1 mg/ml
• 存储缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
• Human Gene ID 1163
• Human Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1163
• Human Swissprot No. P61024
• Human Swissprot Link http://www.uniprot.org/uniprotkb/P61024/entry
• Mouse Gene ID 54124
• Mouse Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54124
• Mouse Swissprot No. P61025
• Mouse Swissprot Link http://www.uniprot.org/uniprot/P61025
• 免疫原 The antiserum was produced against synthesized peptide derived from human CKS1. AA range:10-59
• 特异性 Cks1 Polyclonal Antibody detects endogenous levels of Cks1 protein.
• 稀释度 WB 1:500-1:2000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:20000.Not yet tested in other applications.
• 预测分子量 9kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 Rabbit,IgG
• 背景介绍 CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008],
• 组织表达 Brain,Muscle,Promyelocytic leukemia,Prostate,Tongue,
• 细胞定位 cyclin-dependent protein kinase holoenzyme complex,nucleoplasm,SCF ubiquitin ligase complex,
• 信号通路 Pathways in cancer;Small cell lung cancer;
• 功能 function:Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.,similarity:Belongs to the CKS family.,subunit:Forms a homohexamer that can probably bind six kinase subunits.,
• 纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

图片

	Immunofluorescence analysis of HeLa cells, using CKS1 Antibody. The picture on the right is blocked with the synthesized peptide.
	Western blot analysis of lysates from Jurkat cells, treated with serum 20% 15‘, using CKS1 Antibody. The lane on the right is blocked with the synthesized peptide.
	Western Blot analysis of various cells using Cks1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.

产品详情