产品基本信息

• 产品货号 BD-PT0922
• 别名 CHST9; Carbohydrate sulfotransferase 9; GalNAc-4-O-sulfotransferase 2; GalNAc-4-ST2; GalNAc4ST-2; N-acetylgalactosamine-4-O-sulfotransferase 2
• 产品名称 CHST9 Rabbit Polyclonal Antibody
• 类别 抗原抗体
• 基因名称 CHST9
• 蛋白名称 Carbohydrate sulfotransferase 9
• Clonality Polyclonal
• 推荐应用 IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Mouse
• 浓度 1 mg/ml
• 存储缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
• Human Gene ID 83539
• Human Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83539
• Human Swissprot No. Q7L1S5
• Human Swissprot Link http://www.uniprot.org/uniprotkb/Q7L1S5/entry
• Mouse Gene ID 71367
• Mouse Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71367
• Mouse Swissprot No. Q76EC5
• Mouse Swissprot Link http://www.uniprot.org/uniprot/Q76EC5
• 免疫原 The antiserum was produced against synthesized peptide derived from human CHST9. AA range:361-410
• 特异性 CHST9 Polyclonal Antibody detects endogenous levels of CHST9 protein.
• 稀释度 IHC-P 1:100-1:300, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:20000.Not yet tested in other applications.
• 参考分子量 51kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 Rabbit,IgG
• 背景介绍 The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011],
• 组织表达 Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord.
• 细胞定位 [Isoform 1]: Golgi apparatus membrane ; Single-pass type II membrane protein .; [Isoform 2]: Secreted .
• 功能 caution:It is uncertain whether Met-1 or Met-8 is the initiator.,function:Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin.,similarity:Belongs to the sulfotransferase 2 family.,tissue specificity:Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord.,
• 期货 现货
• 纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

图片

	Immunofluorescence analysis of HUVEC cells, using CHST9 Antibody. The picture on the right is blocked with the synthesized peptide.
	Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CHST9 Antibody. The picture on the right is blocked with the synthesized peptide.

产品详情