PCNA (4B2) Rabbit Monoclonal Antibody
产品基本信息
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产品货号
B2223
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Uniprot ID
P12004
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Gene ID
5111
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别名
ATLD2
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产品名称
PCNA (4B2) Rabbit Monoclonal Antibody
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类别
抗原抗体
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,IF-P,IF-ICC,FCM,IP
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反应种属
Human,Mouse,Rat
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存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
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免疫原
A synthetic peptide of human PCNA
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稀释度
WB 1:1000-1:5000, IHC-P/IF-P 1:100-1:500, IF-ICC 1:100-1:200, FCM 1:50, IP 1:20
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参考分子量
36kDa
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预测分子量
29kDa
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运输及保存条件
-20°C/1 year
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宿主
Rabbit
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同种型
IgG
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背景介绍
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
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纯化
Affinity Purification
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