产品基本信息

• 产品货号 BD-PT0568
• 别名 C3AR1; AZ3B; C3R1; HNFAG09; C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R
• 产品名称 C3aR Rabbit Polyclonal Antibody
• 类别 抗原抗体
• 基因名称 C3AR1
• 蛋白名称 C3a anaphylatoxin chemotactic receptor
• Clonality Polyclonal
• 推荐应用 IHC-P,IF-P,IF-F,IF-ICC,ELISA
• 反应种属 Human,Rat,Mouse
• 浓度 1 mg/ml
• 存储缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
• Human Gene ID 719
• Human Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=719
• Human Swissprot No. Q16581
• Human Swissprot Link http://www.uniprot.org/uniprotkb/Q16581/entry
• Mouse Swissprot No. O09047
• Mouse Swissprot Link http://www.uniprot.org/uniprot/O09047
• 免疫原 The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224
• 特异性 C3aR Polyclonal Antibody detects endogenous levels of C3aR protein.
• 稀释度 IHC-P 1:100-1:300, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:10000.Not yet tested in other applications.
• 参考分子量 54kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 Rabbit,IgG
• 背景介绍 C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016],
• 组织表达 Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
• 细胞定位 Cell membrane; Multi-pass membrane protein.
• 信号通路 Neuroactive ligand-receptor interaction;Complement and coagulation cascades;
• 功能 function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.,
• 期货 现货
• 纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

图片

	Immunofluorescence analysis of COS7 cells, using C3AR1 Antibody. The picture on the right is blocked with the synthesized peptide.
	Immunohistochemistry analysis of paraffin-embedded human brain tissue, using C3AR1 Antibody. The picture on the right is blocked with the synthesized peptide.

产品详情