产品基本信息

• 产品货号 BD-PT0189
• 别名 ALDH1B1; ALDH5; ALDHX; Aldehyde dehydrogenase X; mitochondrial; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1
• 产品名称 ALDH1B1 Rabbit Polyclonal Antibody
• 类别 抗原抗体
• 基因名称 ALDH1B1
• 蛋白名称 Aldehyde dehydrogenase X mitochondrial
• Clonality Polyclonal
• 推荐应用 WB,ELISA
• 反应种属 Human,Monkey
• 浓度 1 mg/ml
• 存储缓冲液 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
• Human Gene ID 219
• Human Gene Link http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=219
• Human Swissprot No. P30837
• Human Swissprot Link http://www.uniprot.org/uniprotkb/P30837/entry
• Mouse Swissprot No. Q9CZS1
• Mouse Swissprot Link http://www.uniprot.org/uniprot/Q9CZS1
• 免疫原 The antiserum was produced against synthesized peptide derived from human ALDH1B1. AA range:311-360
• 特异性 ALDH1B1 Polyclonal Antibody detects endogenous levels of ALDH1B1 protein.
• 稀释度 WB 1:500-1:2000, ELISA 1:20000.Not yet tested in other applications.
• 预测分子量 57kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 Rabbit,IgG
• 背景介绍 This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008],
• 组织表达 Liver, testis and to a lesser extent in brain.
• 细胞定位 Mitochondrion matrix.
• 信号通路 Glycolysis / Gluconeogenesis;Ascorbate and aldarate metabolism;Fatty acid metabolism;Valine; leucine and isoleucine degradation;Lysine degradation;Arginine and proline metabolism;Histidine metabolism;Tryptophan metabolism;beta-Alanine metabolism;Glycerolipid metabolism;Pyruvate metabolism;Propanoate metabolism;Butanoate metabolism;Limonene and pinene degradation;
• 功能 catalytic activity:An aldehyde + NAD(+) + H(2)O = an acid + NADH.,function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer.,tissue specificity:Liver, testis and to a lesser extent in brain.,
• 期货 现货
• 纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

图片

	Western blot analysis of lysates from HepG2 and COS cells, using ALDH1B1 Antibody. The lane on the right is blocked with the synthesized peptide.
	Western Blot analysis of various cells using ALDH1B1 Polyclonal Antibody diluted at 1：1000
	Western Blot analysis of COS7 cells using ALDH1B1 Polyclonal Antibody diluted at 1：1000

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