产品基本信息

• 产品货号 BD-PN0392
• 产品名称 ACSA Rabbit Polyclonal Antibody
• 类别 抗原抗体
• 基因名称 ACSS2 ACAS2
• 蛋白名称 Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)
• Clonality Polyclonal
• 推荐应用 WB,ELISA
• 反应种属 Human,Mouse
• 浓度 1 mg/ml
• 存储缓冲液 Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
• Human Gene ID 55902
• Human Swissprot Link https://www.uniprot.org/uniprotkb/Q9NR19/entry
• Mouse Swissprot No. Q9QXG4
• Mouse Swissprot Link http://www.uniprot.org/uniprot/Q9QXG4
• 免疫原 Synthesized peptide derived from human protein . at AA range: 40-120
• 特异性 ACSA Polyclonal Antibody detects endogenous levels of protein.
• 稀释度 WB 1:500-2000, ELISA 1:5000-20000
• 预测分子量 77kDa
• 运输及保存条件 -20°C/1 year
• 宿主 Rabbit
• 同种型 Rabbit,IgG
• 背景介绍 This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
• 组织表达 Blood,Melanoma,Muscle,Platelet,Skin,Tongue,
• 细胞定位 Cytoplasm, cytosol .
• 信号通路 Glycolysis / Gluconeogenesis;Pyruvate metabolism;Propanoate metabolism;
• 功能 catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,
• 纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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