产品基本信息

• 产品货号 BD-PM6043
• 别名 47 kDa cytokeratin;CK-13;CK13;Cytokeratin 13;Cytokeratin-13;K13;K1C13_HUMAN;Ka13;Keratin 13;Keratin;keratin type I cytoskeletal 13;Keratin-13;Krt-1.13;Krt1-13;KRT13;MGC161462;MGC3781;type I cytoskeletal 13;Type I keratin Ka13;WSN2
• 产品名称 Cytokeratin 13 (3X9) Mouse Monoclonal Antibody
• 类别 抗原抗体
• 基因名称 KRT13
• 蛋白名称 47 kDa cytokeratin;CK-13;CK13;Cytokeratin 13;Cytokeratin-13;K13;K1C13_HUMAN;Ka13;Keratin 13;Keratin;keratin type I cytoskeletal 13;Keratin-13;Krt-1.13;Krt1-13;KRT13;MGC161462;MGC3781;type I cytoskeletal 13;Type I keratin Ka13;WSN2
• 推荐应用 IHC-P,ELISA
• 反应种属 Human
• 制备方法 The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• 存储缓冲液 PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
• Human Swissprot Link https://www.uniprot.org/uniprotkb/P13646/entry
• Mouse Swissprot No. P08730
• Rat Swissprot No. Q6IFV4
• 特异性 The antibody can specifically recognize human CK13 protein. In western blotting of A431 cell lysate, the antibody can label a 50 kDa band corresponding to CK13.
• 稀释度 IHC-P 1:200-400. ELISA 1:500-5000
• 预测分子量 50kD
• 运输及保存条件 -15°C to -25°C/1 year(Do not lower than -25°C)
• 组织表达 Tonsil
• 细胞定位 Cytoplasmic, Membranous
• 功能 disease:Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,online information:Keratin-13 entry,PTM:O-glycosylated; glycans consist of single N-acetylglucosamine residues.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4.,tissue specificity:Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.,
• 纯化 The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

图片

Human cervical squamous cell carcinoma tissue was stained with Anti-Cytokeratin 13 Antibody

产品详情