产品基本信息

• 产品货号 BDAB0059
• 别名 Neuropilin-1,Vascular endothelial cell growth factor 165 receptor,CD304.
• 产品名称 Recombinant Human NRP1 protein
• 类别 病原微生物抗原抗体假病毒
• 推荐应用 Immunogen
• 存储缓冲液 Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
• 特异性 Homo sapiens (Human)
• 参考分子量 72.14 kDa
• 运输及保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
• 宿主 E.coli
• type1 His tag
• 注意事项 NRP1
• limitation For?research?use?only?.
• 背景介绍 Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB . Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development). Regulates mitochondrial iron transport via interaction with ABCB8/MITOSUR.
• 纯化 >90% as determined by SDS-PAGE

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